Padres vs. Guardians: Start Time, Streaming Live, TV Channel, How to Watch - Bleacher Nation (2025)

At PETCO Park on Wednesday, the Cleveland Guardians (2-2) take on Manny Machado and the San Diego Padres (5-0) at 4:10 p.m. ET.

The article below will provide you with everything you need to watch San Diego play Cleveland.

When is Padres vs. Guardians and when does it start?

This matchup between the Padres and Guardians will take place on Wednesday, April 2, 2025. Be ready to see the opening pitch at 4:10 p.m. ET.

Where to watch Padres vs. Guardians

The Padres and Guardians will take to the diamond at PETCO Park for this matchup on April 2, and if you’d like to catch the game live, get your tickets now from Vivid Seats!

What channel is the game on?

You can catch this game live on SDPA, CLEG.

Watch the Padres vs. Guardians live stream on Fubo

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Padres vs. Guardians Game Preview

Monday, the Padres claimed a 7-2 victory over the Guardians, with Kyle Hart (5.0 IP, 2 R, 5 H, 4 K) registering the win for the Padres. Gavin Sheets went 3-for-3 with two doubles and four RBI to lead the offense. Luis Ortiz (4.2 IP, 7 R, 9 H, 2 K) was credited with the loss for the Guardians.

Padres Stats, Odds & Insights (2024)

The Padres won 60.4% of the games last season they were the moneyline favorite (64-42).

San Diego averaged 1.2 home runs per game to rank 10th in MLB with 190 total home runs last season.

Last year the Padres’ .420 slugging percentage ranked seventh-best in baseball.

San Diego had the 12th-ranked team ERA among all MLB pitching staffs (3.86).

Last season Padres pitchers combined for the No. 6 WHIP in MLB (1.222).

Guardians Stats, Odds & Insights (2024)

The Guardians were underdogs 65 times last season and won 29, or 44.6%, of those games.

Cleveland’s 185 home runs ranked 12th in Major League Baseball.

The Guardians were 16th in MLB with a slugging percentage of .395 last season.

Cleveland pitched to a 3.61 ERA last season, which ranked third in baseball.

Guardians pitchers had a 1.202 WHIP last season, fourth-best in the majors.

Padres Key Players to Watch (2024 Stats)

The Padres are sending Dylan Cease (0-0) out for his second start of the season.

In his most recent appearance on Saturday, the right-hander threw 4 1/3 innings against the Atlanta Braves, allowing three earned runs while surrendering four hits.

Machado slugged 29 home runs and collected 105 RBI last season while batting .275.

Jackson Merrill collected 162 hits, posted an OBP of .326, and a .500 SLG.

Luis Arraez hit .314 last season with four home runs and 46 RBI.

Guardians Key Players (2024 Stats)

Ben Lively will get the start for the Guardians, his second of the season.

The right-hander’s last appearance was on Thursday, when he threw five innings, giving up three earned runs while allowing four hits against the Kansas City Royals.

Jose Ramirez racked up 39 home runs and had 118 runs batted in last season.

Steven Kwan hit .292 a season ago with 140 hits.

Carlos Santana hit .238 last season with 26 doubles, 23 home runs and 65 walks.

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Padres vs. Guardians: Start Time, Streaming Live, TV Channel, How to Watch - Bleacher Nation (2025)

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